Experience firsthand the recent transformation of the Rochester Marriott Mayo Clinic. Connected to the Mayo Clinic, the Rochester Marriott Mayo Clinic offers easy access to the city's most popular attractions via the climate-controlled pedestrian subway and skyway. Featuring luxurious bedding and HDTV's, our newly remodeled rooms offer a wealth of upscale amenities. Indulge in shopping at University Square or set out for adventure with biking, fly fishing, and horseback riding nearby. Minneapolis-St. Paul is an easy day trip from the Rochester Marriott. Business travelers working with Rochester Methodist Hospital or other area companies will enjoy the spacious guest rooms with well-lit work desks and high-speed Internet. Host work sessions in the large boardroom of this downtown Rochester Minnesota hotel. Unwind from a busy day in our atrium lobby, DEN! Restaurant and Lobby Bar. Discover the warm, reassuring comfort of the Rochester Marriott Mayo Clinic.