Residence Inn is the favorite choice for "All Suites" extended-stay Vacaville, CA hotels. We're centrally located on I-80 between San Francisco and Sacramento at the entrance to the rolling hills of the Sonoma/Napa Valley Wine Country. This means all the biggest stops in business and leisure are convenient to our hotel in Vacaville, CA. Visit Travis Air Force Base or major corporations such as Genentech and Alza. Explore nearby attractions: Napa Valley wineries, Cache Creek Casino, Anheuser Busch and Six Flags Discovery Kingdom. We're also only 15 minutes to University of California, Davis. Whatever brings you, there's no better choice of hotels in Vacaville, California. Perks include free Wi-Fi, free breakfast, evening social hours, fitness center, indoor/outdoor pool, 24hr Market and guest laundry. Plus, our 78 Vacaville hotel suites are newly renovated with all the comforts of home. Helping guests thrive on overnights, extended-stays and everything in between, choose Residence Inn Vacaville, CA Hotel.