Stay at One of the Best Hotels in Vacaville, CA Nestled among rolling hills and farmland, Vacaville is centrally located between San Francisco and Sacramento. With a convenient location off I-505 and I-80, the Holiday Inn Express & Suites® Vacaville hotel is the perfect choice for all travelers. We are minutes from Travis Air Force Base, University of California - Davis and Napa and Sonoma wine country. Whether you prefer small-town charm or you're exploring Northern California, our hotel's location in Vacaville, CA is ideal. Nearby Fairfield offers beer and candy tasting at the Budweiser Brewery and Jelly Belly Factory. We are just a few blocks from Vacaville Premium Outlets. You can take a day trip to visit the wineries of Napa Valley and Sonoma which are about 30 miles away. Corporate guests find our hotel ideal, as well. We are near many companies, such as Alza and Genentech, and provide quality perks that make your stay comfortable, such as a 24-hour Business Center and free Wi-Fi access throughout the hotel. Our well-equipped meeting facilities can accommodate 94 people. As a 2009 Torch Bearer award-winner, our Vacaville hotel offers the best customer service. We have everything you need, including a Fitness Center, free, hot breakfast, a heated, indoor pool and a whirlpool. Relax on the charming patio and use the grills to cook dinner. We host a "Meet and Greet Social" weekday evenings for you with free beverages and snacks.