Enjoy One of the Top Hotels in Panama City, Florida Just off Highway 22 and within minutes of numerous attractions and businesses, our Holiday Inn Express® hotel is one of the most convenient and comfortable hotels in Panama City, Florida. Our hotel's near Tyndall Air Force Base, making it easy to visit relatives and friends. We're also just 20 minutes from Panama City Beach and Mexico Beach, so you can bring the family out to soak up the sun. Be sure to visit the Panama City Marina, as well, for waterfront dining, one-of-a-kind art galleries and a stroll along the beautiful boardwalk, lined with yachts and charter boats. For corporate travelers, our hotel's Business Center provides a convenient way to catch up on work from the quiet atmosphere of the hotel. Additionally, if you're planning a meeting, be sure to reserve our spacious meeting room, which can accommodate up to 30 guests. You'll also find our hotel convenient to businesses like Eastern Ship Building, Smurfit-Stone and Arizona Chemical. When it comes to hotels near Tyndall Air Force Base, our accommodations rank at the top. Our extra perks will make your trip enjoyable, so relax by the outdoor pool or get a workout in our Fitness Center. Be sure to stop in and fill up on our Express Start Breakfast Bar with delicious items like bacon, eggs and especially our signature cinnamon rolls and 100% Arabica bean coffee. Make your reservations today!