Stay Smart at the Holiday Inn Express® Orangeburg Hotel Southern charm, natural beauty and a friendly staff await you at our Orangeburg hotel, located just minutes from Edisto Memorial Gardens. Because of the city's ideal climate and central location, it is known as a hunter's paradise, a golfer's delight and a nature lover's dream. Business travelers find our hotel's location in Orangeburg, SC a convenient option, as we're close to several area businesses, as well as the Orangeburg Municipal Airport. We offer outstanding corporate services, such as a spacious meeting room and a 24-hour business center featuring free high-speed Internet access, copying, printing and a personal computer. Situated amidst the area's best attractions, our hotel's property in Orangeburg, SC is the perfect place for leisure travelers. Guests can visit a student at South Carolina State, tour the beautiful gardens of Edisto or take a day trip to the state's capitol, Columbia. In addition, we are located just an hour from the beautiful downtown and sandy beaches of Charleston, SC. While you are staying with us in Orangeburg, our hotel provides you with a host of opportunities, such as swimming in an indoor pool, working out in the on-site fitness center or savoring delicious items from our free, hot breakfast bar. When comparing hotels in Orangeburg, SC, make the smart choice and stay with us.