Welcome to BEST WESTERN PLUS On the River!Close to the Mississippi River, our Hannibal hotel is also near the Mark Twain Boyhood Home and Museum so guests can see the inspiration and the beginnings of one of Americas literary greats.Our Hannibal hotel is located in the downtown area, the perfect place for guests to walk around the neighborhood and explore on foot. Were close to shopping, dining and bars, making it as easy for our guests to get the full experience of the region as possible. When youre close to attractions, its easy to make the most of your trip and see it all.Another reason many guests stay at our Hannibal hotel is because they have business to take care of at Hannibal-LaGrange University, only a short distance away. We regularly welcome visiting students, faculty and staff. With free high-speed Internet and an indoor pool and hot tub, youll feel right at home and have everything you need for a seamless trip. July 4th weekend is a big celebration in this area, and many out-of-towners stay at our Hannibal hotel to enjoy the festivities. The Hannibal Caveman baseball team is a source of great pride, and you deserve to stay in cool, comfortable accommodations if youre in town to catch a game. Whether youre here for the Fall Fest, jet skiing or on business, rest assured youll be treated like family here.A few of our regular Hannibal hotel guests are employees of Hannibal Regional Hospital, General Mills, Buckhorn Rubber® or BASF. Even if youre here for a vacation, though, its important to fill up with a hearty all-American breakfast, and its on us. Our free hot breakfast includes your favorites like hot waffles and eggs, pastries and fresh fruits, a selection of cereal and yogurt choices. Complete your meal with 100% Arabica coffee or your juice of choice. Its the best way to get a great day started.Reserve your conveniently located room at BEST WESTERN PLUS On the River today and enjoy the trip!