Our Poughkeepsie Hotel is the Smart Choice When it comes to comfort and convenience among Hudson Valley hotels, the Holiday Inn Express® Poughkeepsie hotel has just what you need while staying in the Hudson Valley. Our hotel's central location is minutes from leading area businesses and attractions, making our accommodations perfect for corporate and leisure travelers. Our Poughkeepsie hotel's proximity to the Culinary Institute of America, IBM, Vassar College, Marist College and St. Francis and Vassar hospitals is a big hit with business travelers, who also appreciate that we offer free Internet access and a modern Business Center. While vacationing in the Hudson Valley, our hotel's guests should make plans to see sights like the Vanderbilt Mansion and FDR Presidential Library, which are just a short drive from us on Route 9. Don't miss Locust Grove, the birthplace of Morse Code inventor Samuel B. Morse, which is located just across the street from us. Since it's a 90-minute train ride to Grand Central Station in New York City, you can make an easy trip into the Big Apple for a day of fun. While staying in Poughkeepsie, our hotel's guests are invited to enjoy our free, hot Express Start Breakfast Bar. We offer an array of delicious items to help you start your day off right. If you want to keep up your workout routine while traveling, then take advantage of our 24-hour Fitness Center. Our Poughkeepsie hotel's staff is ready to welcome you.