Hotel in Biloxi-Ocean Springs, Mississippi Near the Mississippi Gulf Shore Welcome to the Holiday Inn Express Hotel & Suites in Biloxi-Ocean Springs. Our hotel, located right off I-10 and I-110 and 14 miles from the Gulfport-Biloxi International Airport (GPT), is convenient to all that the Gulf coast of Southern Mississippi has to offer. Travelers appreciate how our location makes "Stay Real" a Biloxi-Ocean Springs reality. Vacationers to our smoke-free hotel can enjoy a wide range of area attractions. You can enjoy the beautiful Gulf Beaches only a few miles away. Play golf between business appointments at Shell Landing, a five course gem just minutes away. If you want to experience the Biloxi nightlife, you can go to the Casinos all minutes away from the hotel. Nearby businesses within a half-hour of our hotel include Northrop Grumman, Dupont, Keesler Air Force Base and Chevron. Both the Biloxi Regional Hospital and Mississippi Coast Coliseum are also nearby and convenient. Relieve stress by exercising in our fitness center, or swim and relax at our outdoor pool. If you require Group Meeting facilities we can accommodate up to 75 people. High-speed Internet access is available in our lobby, business center, and all guest rooms. Start the morning off right with our complimentary Express Start breakfast. For business or pleasure, Stay Smart at the Holiday Inn Hotel & Suites, Biloxi-Ocean Springs MS.