Relax at La Crosse, Wisconsin Hotel's Downtown Location Positioned near the Mississippi River and across the street from the La Crosse Center, the Holiday Inn® Hotel & Suites La Crosse welcomes visitors with a courteous staff who strive to make their stay more enjoyable. The hotel's leisure guests love that La Crosse, Wisconsin provides a variety attractions and activities. Whether you want to enjoy the outdoors with a Mississippi River cruise or browse the local art at the Pump House Regional Arts Center, there is something for every interest. Just across the street, the La Crosse Center features a calendar of events that range from top performing music artists to the La Crosse Spartans indoor football league. In La Crosse, Wisconsin, we keep corporate travelers productive by offering free high-speed, wireless Internet access and a 24-hour Business Center with fax, copy and print services. With Trane, Gundersen Lutheran, Franciscan Skemp, UW - La Crosse and Viterbo University all less than four miles from our hotel's location in La Crosse, WI, hotel patrons also spend less time getting to meetings and clients. In addition to area attractions, on-site amenities keep guests entertained. Visitors enjoy a heated, indoor pool and an over-sized hot tub, a Fitness Center and a complimentary shuttle service to and from transportation centers. Book a room today in La Crosse, WI, and see how our hotel provides quality at a price you can afford.